This is a concentrate, meaning that there are many times as much ORMUS/High Spin Platinum metal group colloids as there is in an equal amount of the untrapped spring water at its source. Starting doseage is one ounce twice daily, and we recommend you stay at this doseage level for several days if you are just starting to take these substances. Some people experience heat flashes and excess heat, difficulty sleeping or excessive sleepiness and often describe a ringing or buzzing in the ears (some do not). We normally recommend a reduction in dose if you experience such effects, at least temporarily. Increase as desired or tolerated.